Alvaro Morata, Mario Mandzukic and Juan Cuadrado could start in a 4-3-3 formation for Juventus against Bayern Munich.
The second leg in the Champions League Round of 16 kicks off on Wednesday at 19.45 GMT.
It ended 2-2 in Turin, so the Bianconeri must either win or play a score draw of 3-3 and above to qualify for the quarter-finals.
Juve have huge injury problems, missing Paulo Dybala, Giorgio Chiellini, Claudio Marchisio and Martin Caceres.
Mandzukic requires a fitness test, as he skipped training for two days, but is expected to start in a new 4-3-3 formation.
Cuadrado and Morata complete the trident, while Hernanes is the creative centre flanked by Paul Pogba and Sami Khedira.
Patrice Evra is likely to start rather than Alex Sandro at left-back.
Bayern Munich also have injury concerns and Arjen Robben remains a doubt after coming down with flu symptoms.
Jerome Boateng and Holger Badstuber are long-term absentees, while Javi Martinez is also unlikely to feature after only recently returning from injury.
The only expected changes from the side that started in Turin are Medhi Benatia into the back four for Bernat, returning David Alaba to his more habitual left-back role, and Franck Ribery in for Robben.
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